منابع مشابه
Propranolol withdrawal syndrome - why?
FEW WHO HAVE WITNESSED the propranolol withdrawal phenomenon would deny its existence. The syndrome, which comprises the development of ventricular arrhythmias, severe angina, myocardial infarction and even death soon after sudden cessation of propranolol therapy, was first described in a series of case reports.' Perhaps the most convincing evidence was obtained by Miller et al.,6 who noted a 5...
متن کاملThe pathogenesis of propranolol-withdrawal syndrome in essential hypertension.
1. In hypertension, the beta-adrenoreceptor-blocker-withdrawal syndrome comprises tachycardia, sweating, tremor and general malaise, symptoms resembling thyrotoxicosis. 2. The effect of abrupt cessation of propranolol on serum concentrations of thyroxine (T4) and triiodothyronine (T3) was therefore investigated in five patients with uncomplicated essential hypertension, treated with propranolol...
متن کاملMechanism of propranolol withdrawal phenomena.
Nine patients on chronic treatment with propranolol for essential hypertension for 3 months or longer were studied after abrupt discontinuation of the drug. Each patient demonstrated transient supersensitivity to the chronotropic effects of isoproterenol, beginning 2--6 days (median 4 days) after propranolol withdrawal, lasting for 3--13 days (median 6 days), with the maximum sensitivity on day...
متن کاملPlasma and atrial propranolol after preoperative withdrawal.
Of 34 patients scheduled for aortocoronary bypass operations who were withdrawn from chronic propranolol therapy between 18 and 48 hours before anesthesia and operation, propranolol was detected in the plasma of nine and in atrial tissue of five patients. Higher plasma levels were associated with higher propranolol intake and with shorter time of withdrawal. In 15 patients withdrawn preoperativ...
متن کاملEffect of propranolol on acute withdrawal tremor in alcoholic patients.
The effect of the beta-adrenergic blocking agent propranolol was tested on positional tremor occurring during acute alcohol withdrawal using a double-blind crossover method and electrical recording of tremor amplitude and frequency. The difference between the effects of propranolol and placebo was not significant.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation
سال: 1978
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.58.2.202